CI

At a glance

ClinicalIndex Comparison Record
Phase 2Completed· 305 enrolled
Drug / intervention
BioThrax +2 morebiological
Likely dose
Not stated in record
Structured eligibility isn't available for this trial yet — see the full criteria in the Eligibility tab below.

Standardized by ClinicalIndex from the ClinicalTrials.gov record · verify against the source.

Search/NCT03518125
NCT03518125Phase 2Completed

Randomized, Active-Comparison, Double-Blind, Phase 2 Study to Assess the Safety and Immunogenicity of Anthrax Vaccine Adsorbed (BioThrax®) Without and With CPG 7909 Adjuvant (AV7909 Anthrax Vaccine), Using a Post-Exposure Prophylaxis Dosing Regimen in Adults 66 Years of Age or Older in Stable Health in Comparison to Adults 18-50 Years of Age in Stable Health

Biomedical Advanced Research and Development Authority·interventional·Posted May 8, 2018·Updated Jul 21, 2020

In Brief

A Phase 2 clinical trial evaluating BioThrax, AV7909, and 1 other intervention for Anthrax. Completed, enrolled 305 participants across 4 sites.

Detailed Summary

This study is designed to assess the safety and ability of BioThrax and AV7909 anthrax vaccines to generate an immune response in adults ≥ 66 years of age in stable health in comparison to adults 18-50 years of age in stable health.

Study Details

Study Typeinterventional
Allocation--
Masking--
Primary Purpose--
ConditionsAnthrax
CountriesUnited States
CollaboratorsRho, Inc.

Timeline

Phase 2CompletedFinished
20192020202120222023202420252026
First PostedMay 8, 2018
Enrollment StartMay 9, 2018
Primary CompletionJan 14, 2019
Study CompletionDec 9, 2019
TodayJul 2, 2026
Enrollment to primary: 8 monthsPosted 8.2 years ago

Interventions

BioThraxbiological

Other Names: Anthrax Vaccine Adsorbed (AVA)

AV7909biological

Anthrax Vaccine Absorbed plus CPG 7909 Adjuvant

Sodium chloride injection USP, 0.9% (placebo)drug

Other Names: Saline Solution