CI

At a glance

ClinicalIndex Comparison Record
Phase 2Completed· 192 enrolled
Drug / intervention
ASTX029 +1 moredrug
Likely dose
Not stated in record
Structured eligibility isn't available for this trial yet — see the full criteria in the Eligibility tab below.

Standardized by ClinicalIndex from the ClinicalTrials.gov record · verify against the source.

Search/NCT03520075
NCT03520075Phase 2Completed

A Phase 1-2 Study of the Safety, Pharmacokinetics, and Activity of ASTX029 in Subjects With Advanced Solid Tumors

Taiho Oncology, Inc.·interventional·Posted May 9, 2018·Updated Jul 3, 2025

In Brief

A Phase 2 clinical trial evaluating ASTX029 for Solid Tumor, Adult. Completed, enrolled 192 participants across 31 sites in 4 countries.

Detailed Summary

This study is a first-in-human, open-label, multicenter, Phase 1-2 study to assess the safety, pharmacokinetics, pharmacodynamics, and preliminary clinical activity of ASTX029 administered orally to participants with advanced solid malignancies who are not candidates for approved or available therapies.

Study Details

Study Typeinterventional
Allocation--
Masking--
Primary Purpose--
CountriesFrance, Spain, United Kingdom, United States
Collaborators--

Timeline

Phase 2CompletedFinished
20192020202120222023202420252026
First PostedMay 9, 2018
Enrollment StartMay 7, 2018
Primary CompletionAug 1, 2024
Study CompletionMar 3, 2025
TodayJul 2, 2026
Enrollment to primary: 6.2 yearsPosted 8.1 years ago

Interventions

ASTX029drug

PiB

ASTX029drug

Tablet