CI

At a glance

ClinicalIndex Comparison Record
Phase 2Completed· 62 enrolled
Drug / intervention
Tacrolimus +1 moredrug
Likely dose
Not stated in record
Structured eligibility isn't available for this trial yet — see the full criteria in the Eligibility tab below.

Standardized by ClinicalIndex from the ClinicalTrials.gov record · verify against the source.

Search/NCT03527238
NCT03527238Phase 2Completed

Optimizing Immunosuppression Drug Dosing Via Phenotypic Precision Medicine

University of Florida·interventional·Posted May 17, 2018·Updated Dec 10, 2021

In Brief

A Phase 2 clinical trial evaluating PPM-based Computation Assisted Drug Dosing and Tacrolimus for Liver Transplant and Kidney Transplant. Completed, enrolled 62 participants across 3 sites in 2 countries.

Detailed Summary

Clinical trial applying Phenotypic Precision Medicine (PPM) to tacrolimus dosing in liver and/or kidney transplant recipients to show improvement in maintaining drug trough levels within the target range.

Study Details

Study Typeinterventional
Allocation--
Masking--
Primary Purpose--
CountriesSingapore, United States

Timeline

Phase 2CompletedFinished
20192020202120222023202420252026
First PostedMay 17, 2018
Enrollment StartSep 21, 2018
Primary CompletionJun 2, 2020
Study CompletionAug 31, 2021
TodayJul 2, 2026
Enrollment to primary: 1.7 yearsPosted 8.1 years ago

Interventions

PPM-based Computation Assisted Drug Dosingother

Tacrolimus dosing based on application of PPM.

Tacrolimusdrug

Dosing of calcineurin inhibitor, tacrolimus