CI

At a glance

ClinicalIndex Comparison Record
N/ACompleted· 10 enrolled
Drug / intervention
Virtual Heart Guided Ablationdevice
Likely dose
Not stated in record
Structured eligibility isn't available for this trial yet — see the full criteria in the Eligibility tab below.

Standardized by ClinicalIndex from the ClinicalTrials.gov record · verify against the source.

Search/NCT03536052
NCT03536052N/ACompleted

Ablation at Virtual-hEart pRedicted Targets for VT

Johns Hopkins University·interventional·Posted May 24, 2018·Updated Feb 5, 2026

In Brief

A clinical study evaluating Virtual Heart Guided Ablation for Ventricular Tachycardia and Ischemic Cardiomyopathy. Completed, enrolled 10 participants across 1 site.

Detailed Summary

The goal of this study is to test the efficacy of the new imaging/simulation ("virtual heart") approach for determining the optimal ablation sites in patients with VT, which render post-infarction VT non-inducible. The study will test both the acute outcome of the ablation procedure, and the effect the use of the predicted targets has upon procedure time.

Study Details

Study Typeinterventional
Allocation--
Masking--
Primary Purpose--
CountriesUnited States
Collaborators--

Timeline

N/ACompletedFinished
20192020202120222023202420252026
First PostedMay 24, 2018
Enrollment StartSep 26, 2022
Primary CompletionDec 1, 2025
TodayJul 2, 2026
Enrollment to primary: 3.2 yearsPosted 8.1 years ago

Interventions

Virtual Heart Guided Ablationdevice

If a good quality cardiac MRI is obtained and a virtual heart model with the ablation targets is generated, the operating physician will merge the virtual heart lesion map to the invasive electroanatomical navigation system. After the patient has been catheterized, an attempt should be made to induce VT. The physician should then navigate the catheter to each of the ablation targets specified, and place a lesion as per his or her training and experience, confirming when done that the lesion marker in the mapping system coincides with the target. This will be done for each lesion.