CI

At a glance

ClinicalIndex Comparison Record
Phase 2Completed· 44 enrolled
Drug / intervention
Levosimendan +1 moredrug
Likely dose
Levosimendan 2.5 mgfrom record
Structured eligibility isn't available for this trial yet — see the full criteria in the Eligibility tab below.

Standardized by ClinicalIndex from the ClinicalTrials.gov record · verify against the source.

Search/NCT03541603
NCT03541603Phase 2Completed

A Double-Blind, Randomized, Placebo-Controlled Study of Levosimendan in Pulmonary Hypertension Patients With Heart Failure With Preserved Left Ventricular Ejection Fraction (PH-HFpEF)

Tenax Therapeutics, Inc.·interventional·Posted May 30, 2018·Updated Nov 20, 2024

In Brief

A Phase 2 clinical trial evaluating Levosimendan and Matching Placebo for Hypertension Pulmonary Secondary and 2 related conditions. Completed, enrolled 44 participants across 16 sites.

Detailed Summary

Phase 2 study to evaluate the efficacy and safety of intermittent levosimendan compared with placebo in hemodynamic improvement with exercise in PH-HFpEF subjects

Study Details

Study Typeinterventional
Allocation--
Masking--
Primary Purpose--
CountriesUnited States
Collaborators--

Timeline

Phase 2CompletedFinished
20192020202120222023202420252026
First PostedMay 30, 2018
Enrollment StartNov 14, 2018
Primary CompletionApr 7, 2020
TodayJul 2, 2026
Enrollment to primary: 1.4 yearsPosted 8.1 years ago

Interventions

Levosimendandrug

A sterile 2.5 mg/mL concentrate solution that is diluted in 5% Dextrose or 0.9 Normal Saline to achieve a 50 microgram/min solution for infusion

Matching Placebodrug

A sterile 2.5mg/mL concentrate solution that is diluted in 5% Dextrose or 0.9 Normal Saline to achieve a 50 microgram/min solution for infusion