CI

At a glance

ClinicalIndex Comparison Record
Phase 3Completed· 345 enrolled
Drug / intervention
Brexpiprazole +1 moredrug
Likely dose
Not stated in record
Structured eligibility isn't available for this trial yet — see the full criteria in the Eligibility tab below.

Standardized by ClinicalIndex from the ClinicalTrials.gov record · verify against the source.

Search/NCT03548584
NCT03548584Phase 3Completed

A Phase 3, 12-Week, Multicenter, Randomized, Double-blind, Placebo-controlled, 2-Arm, Fixed-dose Trial to Evaluate the Efficacy, Safety, and Tolerability of Brexpiprazole (OPC-34712) in the Treatment of Subjects With Agitation Associated With Dementia of the Alzheimer's Type

Otsuka Pharmaceutical Development & Commercialization, Inc.·interventional·Posted Jun 7, 2018·Updated Sep 18, 2023

In Brief

A Phase 3 clinical trial evaluating Brexpiprazole and Placebo for Agitation Associated With Alzheimer's Dementia and Alzheimer Dementia. Completed, enrolled 345 participants across 1 site.

Detailed Summary

This study compares the efficacy of 2 doses of brexpiprazole with placebo in participants with agitation associated with dementia of the Alzheimer's type.

Study Details

Study Typeinterventional
Allocation--
Masking--
Primary Purpose--
CountriesUnited States
CollaboratorsH. Lundbeck A/S

Timeline

Phase 3CompletedFinished
20192020202120222023202420252026
First PostedJun 7, 2018
Enrollment StartMay 16, 2018
Primary CompletionMay 23, 2022
Study CompletionJun 1, 2022
TodayJul 2, 2026
Enrollment to primary: 4.0 yearsPosted 8.1 years ago

Interventions

Brexpiprazoledrug

Oral tablets

Placeboother

Oral tablets