CI

At a glance

ClinicalIndex Comparison Record
N/ACompleted· 23 enrolled
Drug / intervention
Robust Radiotherapy planning +1 moreother
Likely dose
Not stated in record
Structured eligibility isn't available for this trial yet — see the full criteria in the Eligibility tab below.

Standardized by ClinicalIndex from the ClinicalTrials.gov record · verify against the source.

Search/NCT03552965
NCT03552965N/ACompleted
CompareCT.gov

Prospective Randomized Pilot Clinical Trial of Margin-Based Vs. Robust Photon Radiotherapy Planning in Intensity-Modulated Radiation Therapy of Squamous-Cell Carcinoma of the Head and Neck

University of Arkansas·interventional·Posted Jun 12, 2018·Updated Sep 2, 2025

In Brief

A clinical study evaluating Robust Radiotherapy planning and Margin-Based Radiotherapy planning for Squamous Cell Carcinoma of the Head and Neck. Completed, enrolled 23 participants across 1 site.

Detailed Summary

This is a research study to evaluate the quality of life and amount of dry mouth experienced as a result of radiotherapy in subjects who have squamous cell carcinoma of the head and neck (HN-SQCC). This study will compare the side effects experienced based on the method to plan radiotherapy, Margin Based or Robust.

Study Details

Study Typeinterventional
Allocation--
Masking--
Primary Purpose--
ConditionsSquamous Cell Carcinoma of the Head and Neck
CountriesUnited States
Collaborators--

Timeline

N/ACompletedFinished
20192020202120222023202420252026
First PostedJun 12, 2018
Enrollment StartJun 19, 2018
Primary CompletionMar 9, 2024
Study CompletionFeb 1, 2025
TodayJul 2, 2026
Enrollment to primary: 5.7 yearsPosted 8.1 years ago

Interventions

Robust Radiotherapy planningother

Investigator will plan Intensity-Modulated Radiation Therapy (IMRT) using calculations that minimize the dose of radiation to normal tissue

Margin-Based Radiotherapy planningother

Investigator will plan Intensity-Modulated Radiation Therapy (IMRT) using calculations that introduce a margin to the target area