CI

At a glance

ClinicalIndex Comparison Record
N/ACompleted· 59 enrolled
Drug / intervention
Coagulation factor levelsother
Likely dose
Not stated in record
Structured eligibility isn't available for this trial yet — see the full criteria in the Eligibility tab below.

Standardized by ClinicalIndex from the ClinicalTrials.gov record · verify against the source.

Search/NCT03555383
NCT03555383N/ACompleted
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Hemostasis Kinetics During Bloodless Liver Transplantation

Semmelweis University·observational·Posted Jun 13, 2018·Updated Sep 2, 2020

In Brief

An observational study evaluating Coagulation factor levels for Blood Loss, Postoperative and 2 related conditions. Completed, enrolled 59 participants across 1 site.

Detailed Summary

This study evaluates the hemostatic changes defined as hemostasis reserve capacity (HRC) in the first perioperative 48 hours of bloodless liver transplanted patients.

Study Details

Study Typeobservational
Allocation--
Masking--
Primary Purpose--
ConditionsBlood Loss, Postoperative, Liver Transplant, Hemostatic Disorder
CountriesHungary
Collaborators--

Timeline

N/ACompletedFinished
201820192020202120222023202420252026
First PostedJun 13, 2018
Enrollment StartAug 1, 2017
Primary CompletionAug 1, 2020
Study CompletionAug 31, 2020
TodayJul 2, 2026
Enrollment to primary: 3 yearsPosted 8.1 years ago

Interventions

Coagulation factor levelsother

The minimal functional hemostasis reserve capacity are defined by triggers as hematocrit: 27%, platelets: 30 G/l, Fibrinogen (FI): 1g/l, FII-FV-FVII-FX: 30%, Antithrombin III: 40%, FXIII: 60% levels. The estimate blood volume methodology is used for to determine the amount of allowable blood loss in volume (ml) that does not require replacement based on current and trigger levels. The individualized pyramid of intervention defined as hemostasis reserve capacity are followed at every studied patient. All measurements and calculations are performed before liver transplantation (T1), at arrival on Intensive Care Unit (T2) and 12-24-48 hours after liver transplantation (T3-4-5).