CI

At a glance

ClinicalIndex Comparison Record
Phase 3Completed· 598 enrolled
Drug / intervention
Benralizumabbiological
Likely dose
Not stated in record
Structured eligibility isn't available for this trial yet — see the full criteria in the Eligibility tab below.

Standardized by ClinicalIndex from the ClinicalTrials.gov record · verify against the source.

Search/NCT03557307
NCT03557307Phase 3Completed

PONENTE: A Multicenter, Open-label, Phase 3b Efficacy and Safety Study of Benralizumab 30 mg Administered Subcutaneously to Reduce Oral Corticosteroid Use in Adult Patients With Severe Eosinophilic Asthma on High Dose Inhaled Corticosteroid Plus Long-acting β2 Agonist and Chronic Oral Corticosteroid Therapy

AstraZeneca·interventional·Posted Jun 15, 2018·Updated Jun 6, 2023

In Brief

A Phase 3 clinical trial evaluating Benralizumab for Asthma. Completed, enrolled 598 participants across 144 sites in 17 countries.

Detailed Summary

This is a study designed to evaluate efficacy and safety of Benralizumab in reducing the Oral Corticosteroid (OCS) use in adult patients with severe asthma who are receiving OCS with or without additional asthma controller medications.

Study Details

Study Typeinterventional
Allocation--
Masking--
Primary Purpose--
ConditionsAsthma
CountriesArgentina, Belgium, Brazil, Canada, Colombia, Denmark, France, Germany, Italy, Mexico, Poland, Russia, Spain, Sweden, Taiwan, United Kingdom, United States
Collaborators--

Timeline

Phase 3CompletedFinished
20192020202120222023202420252026
First PostedJun 15, 2018
Enrollment StartAug 1, 2018
Primary CompletionApr 16, 2021
Study CompletionMar 24, 2022
TodayJul 2, 2026
Enrollment to primary: 2.7 yearsPosted 8.0 years ago

Interventions

Benralizumabbiological

Benralizumab subcutaneous injection