CI

At a glance

ClinicalIndex Comparison Record
Phase 1Completed· 34 enrolled
Drug / intervention
Magrolimab +1 moredrug
Likely dose
Not stated in record
Structured eligibility isn't available for this trial yet — see the full criteria in the Eligibility tab below.

Standardized by ClinicalIndex from the ClinicalTrials.gov record · verify against the source.

Search/NCT03558139
NCT03558139Phase 1Completed

A Phase 1b Trial of Hu5F9-G4 in Combination With Avelumab in Solid Tumor Patients and Checkpoint-Inhibitor-Naive Ovarian Cancer Patients Who Progress Within 6 Months of Prior Platinum Chemotherapy

Gilead Sciences·interventional·Posted Jun 15, 2018·Updated Apr 1, 2024

In Brief

A Phase 1 clinical trial evaluating Magrolimab and Avelumab for Ovarian Cancer. Completed, enrolled 34 participants across 6 sites.

Detailed Summary

The primary objectives of this study are to investigate the safety and tolerability of magrolimab in combination with avelumab in participants with advanced solid tumors and to confirm the safety and tolerability of this combination and evaluate the anti-tumor activity in participants with checkpoint inhibitor-naive ovarian cancer, fallopian tube cancer, and primary peritoneal carcinoma who have previously progressed within 1-6 months of receiving platinum chemotherapy.

Study Details

Study Typeinterventional
Allocation--
Masking--
Primary Purpose--
ConditionsOvarian Cancer
CountriesUnited States

Timeline

Phase 1CompletedFinished
20192020202120222023202420252026
First PostedJun 15, 2018
Enrollment StartMay 23, 2018
Primary CompletionDec 3, 2020
TodayJul 2, 2026
Enrollment to primary: 2.5 yearsPosted 8.0 years ago

Interventions

Magrolimabdrug

Administered intravenously

Avelumabdrug

Administered intravenously