CI

At a glance

ClinicalIndex Comparison Record
N/ACompleted· 360 enrolled
Drug / intervention
Celebrex +5 moredrug
Likely dose
Celebrex 0.2gfrom record
Structured eligibility isn't available for this trial yet — see the full criteria in the Eligibility tab below.

Standardized by ClinicalIndex from the ClinicalTrials.gov record · verify against the source.

Search/NCT03563690
NCT03563690N/ACompleted

Different Kinds of Acupuncture Treatment for Knee Osteoarthritis:a Multicentre Randomised Controlled Trial

Zhejiang Chinese Medical University·interventional·Posted Jun 20, 2018·Updated Jun 8, 2023

In Brief

A clinical study evaluating treatment1, treatment2, and 4 other interventions for Knee Osteoarthritis. Completed, enrolled 360 participants across 1 site.

Detailed Summary

Knee osteoarthritis (KOA) a chronic disease with symptoms of persistent pain or rest pain , joint stiffness, numbness, limitation of activity and even disability, with significant associated costs and effects on individuals' life quality. Acupuncture as an approach for the management of chronic pain, is receiving increasing recognition from both the public and professionals. The aim of this study is to indicate the effects of three commonly used acupuncture treatments for KOA.

Study Details

Timeline

N/ACompletedFinished
20192020202120222023202420252026
First PostedJun 20, 2018
Enrollment StartJul 3, 2018
Primary CompletionOct 28, 2021
Study CompletionDec 31, 2022
TodayJul 2, 2026
Enrollment to primary: 3.3 yearsPosted 8.0 years ago

Interventions

treatment1other

1. Acupoints:Liangqiu(ST34),Xuehai(SP10),Neixiyan(EX-LE4),Dubi(ST35),Yanglingquan (GB34)and Yinlingquan (SP9) 2. operation: the needles will be manipulated using techniques including lifting, thrusting, twisting, and rotating, until De Qi is achieved for 30 minutes.

treatment2other

1. Acupoints:Needling points are the same to the above group 2. operation: The electrode will be connected Neixiyan (EX-LE4) and Dubi (ST35) and electrode wire will be connected to the electro-acupuncture apparatus using dilatational wave with a frequency of 2/100 Hz, the current intensity is within participants'tolerance, for 30 minutes.

treatment3other

1. Acupoints:treating points are the same to the above group 2. Operation: During treatment, participants will choose to sit with knee buckling natural 90 degrees ,with the affected knee(s) exposed. Mild moxibustion are applied at the distance of 2-3 cm away from the skin of both the Neixiyan (EX-LE4) and Dubi (ST35) for 30 minutes.

treatment4other

1. Acupoints:Needling points are the same to the above group 2. Operation: Warm-needling acupuncture are applied at both Neixiyan (EX-LE4) and Dubi (ST35). That is to insert one zhuang(about 2cm)of Huai Qing Ai on the top of the needle, and burn the moxa at the lower end ,each acupoint applied 2 Zhuang for 30 minutes.

treatment5other

1. points:Sham Liangqiu(ST34),Sham Xuehai(SP10), Sham Neixiyan(EX-LE4), Sham Yanglingquan(GB34),Sham Yinlingquan (SP9) 2. Operation: Sham acupuncture with non-meridian and non-acupoint needling method, respectively acupuncture 1cm away lateral to the above sham acupoints with a 0.18 \* 25mm single-use needle with the depth of 1-2mm.

Celebrexdrug

Drug: Celebrex (Celebrex, Capsules, Pfizer Pharmaceuticals Ltd), which will be applied 1 time daily( taken 0.2g one time orally ) Time of treatment :4 weeks Other Name: celecoxib