CI

At a glance

ClinicalIndex Comparison Record
N/ACompleted· 63 enrolled
Drug / intervention
Ropivacaine 0.5% Injectable Solution +2 moredrug
Likely dose
Not stated in record
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Search/NCT03563963
NCT03563963N/ACompleted

Evaluating Ropivacaine and Lidocaine in the Endotracheal Tube Cuff on Post-Operative Sore Throat Incidence and Severity - A Randomized Clinical Trial

University of Saskatchewan·interventional·Posted Jun 20, 2018·Updated Jan 17, 2019

In Brief

A clinical study evaluating Ropivacaine 0.5% Injectable Solution, Lidocaine 2% Preservative-Free Injectable Solution, and 1 other intervention for Pharyngitis and 4 related conditions. Completed, enrolled 63 participants across 2 sites.

Detailed Summary

In elective gynecology and general surgery patients age 18 and over requiring endotracheal tube (ETT) intubation, what is the efficacy of ropivacaine 0.5% vs. lidocaine 2% as the medium to inflate the ETT cuff, compared to the standard of air, in reducing the incidence and severity of POST on post-op day one?

Study Details

Study Typeinterventional
Allocation--
Masking--
Primary Purpose--
CountriesCanada
Collaborators--

Timeline

N/ACompletedFinished
20192020202120222023202420252026
First PostedJun 20, 2018
Enrollment StartAug 1, 2018
Primary CompletionSep 30, 2018
TodayJul 2, 2026
Enrollment to primary: 2 monthsPosted 8.0 years ago

Interventions

Ropivacaine 0.5% Injectable Solutiondrug

Ropivacaine 0.5% will used to inflate the endotracheal tube cuff using the stethoscope guided inflation technique described by Kumar and Hirsch (2). The anesthesiologist will documented the volume in millilitres instilled into the cuff to create a seal. Once a seal was created the anesthesiologist will documented the ETT cuff pressure. If an endotracheal cuff leak occurred during the surgical procedure, the randomized solution was used to inflate the cuff.

Lidocaine 2% Preservative-Free Injectable Solutiondrug

Lidocaine 2% will used to inflate the endotracheal tube cuff using the stethoscope guided inflation technique described by Kumar and Hirsch (2). The anesthesiologist will documented the volume in millilitres instilled into the cuff to create a seal. Once a seal was created the anesthesiologist will documented the ETT cuff pressure. If an endotracheal cuff leak occurred during the surgical procedure, the randomized solution was used to inflate the cuff.

Airother

Air will used to inflate the endotracheal tube cuff using the stethoscope guided inflation technique described by Kumar and Hirsch (2). The anesthesiologist will documented the volume in millilitres instilled into the cuff to create a seal. Once a seal was created the anesthesiologist will documented the ETT cuff pressure. If an endotracheal cuff leak occurred during the surgical procedure, the randomized solution was used to inflate the cuff.