At a glance
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A Pilot Study to Assess Lactate and Bicarbonate Detection Within Malignant Brain Tumors Using [1-13C]-Pyruvate DNP Magnetic Resonance Spectroscopy (MRS)
In Brief
A Phase 1 clinical trial evaluating Gadolinium, Hyperpolarized Carbon C 13 Pyruvate, and 2 other interventions for Malignant Central Nervous System Neoplasm and Metastatic Malignant Neoplasm in the Central Nervous System. Completed, enrolled 9 participants across 1 site.
Detailed Summary
This early phase I trial studies how well hyperpolarized carbon C 13 pyruvate magnetic resonance imaging works in detecting lactate and bicarbonate in participants with central nervous system tumors. Hyperpolarized carbon C 13 pyruvate magnetic resonance imaging may be used to measure the metabolic state of malignant brain tumors.
Study Details
Timeline
Interventions
gadolinium enhanced MRI
Given IV
Undergo MRI
Undergo MRSI