CI

At a glance

ClinicalIndex Comparison Record
Phase 3Completed· 122 enrolled
Drug / intervention
Revefenacin +2 moredrug
Likely dose
Not stated in record
Structured eligibility isn't available for this trial yet — see the full criteria in the Eligibility tab below.

Standardized by ClinicalIndex from the ClinicalTrials.gov record · verify against the source.

Search/NCT03573817
NCT03573817Phase 3Completed

A Phase 3b, 42-day, Randomized, Double-Blind, Placebo Controlled, Parallel Group Study to Evaluate the Safety and Tolerability of Nebulized Revefenacin and Nebulized Formoterol Fumarate (PERFOROMIST®) Administered in Sequence and as a Combined Solution in Subjects With Chronic Obstructive Pulmonary Disease

Mylan Inc.·interventional·Posted Jun 29, 2018·Updated Feb 24, 2022

In Brief

A Phase 3 clinical trial evaluating Revefenacin, Placebo, and 1 other intervention for Chronic Obstructive Pulmonary Disease (COPD). Completed, enrolled 122 participants across 12 sites.

Detailed Summary

The primary objective of the study was to characterize the safety and tolerability of once-daily revefenacin inhalation solution when dosed sequentially with twice-daily formoterol inhalation solution (PERFOROMIST®) compared to PERFOROMIST®, in a population of participants with moderate-to-very severe Chronic Obstructive Pulmonary Disease (COPD) over 21 days.

Study Details

Study Typeinterventional
Allocation--
Masking--
Primary Purpose--
CountriesUnited States

Timeline

Phase 3CompletedFinished
20192020202120222023202420252026
First PostedJun 29, 2018
Enrollment StartMay 31, 2018
Primary CompletionSep 25, 2018
TodayJul 2, 2026
Enrollment to primary: 4 monthsPosted 8.0 years ago

Interventions

Revefenacindrug

Revefenacin is administered via a nebulizer.

Placebodrug

Placebo version of Revefenacin is administered via a nebulizer.

Formoteroldrug

Administered sequentially in both revefenacin and placebo arms using a nebulizer.