CI

At a glance

ClinicalIndex Comparison Record
Phase 3Completed· 924 enrolled
Drug / intervention
Daridorexant +1 moredrug
Likely dose
Not stated in record
Structured eligibility isn't available for this trial yet — see the full criteria in the Eligibility tab below.

Standardized by ClinicalIndex from the ClinicalTrials.gov record · verify against the source.

Search/NCT03575104
NCT03575104Phase 3Completed

Multi-center, Double-blind, Randomized, Placebo-controlled, Parallel-group, Polysomnography Study to Assess the Efficacy and Safety of ACT-541468 in Adult and Elderly Subjects With Insomnia Disorder

Idorsia Pharmaceuticals Ltd.·interventional·Posted Jul 2, 2018·Updated Mar 25, 2022

In Brief

A Phase 3 clinical trial evaluating Daridorexant and Placebo for Insomnia Disorder. Completed, enrolled 924 participants across 86 sites in 11 countries.

Detailed Summary

The main purpose of this study is to assess efficacy and safety of ACT-541468 (daridorexant) in adult and elderly subjects with insomnia disorder. Efficacy will be evaluated on objective and subjective sleep parameters.

Study Details

Study Typeinterventional
Allocation--
Masking--
Primary Purpose--
CountriesBelgium, Bulgaria, Canada, Czechia, Finland, France, Germany, Hungary, South Korea, Sweden, United States
Collaborators--

Timeline

Phase 3CompletedFinished
20192020202120222023202420252026
First PostedJul 2, 2018
Enrollment StartMay 29, 2018
Primary CompletionApr 9, 2020
Study CompletionMay 14, 2020
TodayJul 2, 2026
Enrollment to primary: 1.9 yearsPosted 8 years ago

Interventions

Daridorexantdrug

Daridorexant will be administered as tablets, orally, once daily in the evening.

Placeboother

Matching placebo will be administered as tablets, orally, once daily in the evening.