CI

At a glance

ClinicalIndex Comparison Record
Phase 2Completed· 84 enrolled
Drug / intervention
Testosterone Undecanoate +1 moredrug
Likely dose
Not stated in record
Structured eligibility isn't available for this trial yet — see the full criteria in the Eligibility tab below.

Standardized by ClinicalIndex from the ClinicalTrials.gov record · verify against the source.

Search/NCT03576001
NCT03576001Phase 2Completed

Effect of a Multimodality Intervention to Improve Function and Metabolism in Spinal Cord Injury

Brigham and Women's Hospital·interventional·Posted Jul 3, 2018·Updated May 7, 2026

In Brief

A Phase 2 clinical trial evaluating Testosterone Undecanoate and hybrid exercise for Spinal Cord Injuries. Completed, enrolled 84 participants across 1 site.

Detailed Summary

The proposed phase 2 trial a randomized, placebo-controlled, parallel group trial in persons with cervical or thoracic SCI, AIS grade A, B, C, or D, 6 months or later after injury. The trial will test the hypothesis that a Home-Based Multimodality Functional Recovery and Metabolic Health Enhancement Program that addresses multiple pathophysiologic factors in SCI and includes functional electrical stimulation during leg cycling (FES-LC) plus arm ergometry and an androgen will be more efficacious than functional electrical stimulation during leg cycling (FES-LC) plus arm ergometry plus placebo in improving aerobic capacity, function, metabolism, bone health, and wellbeing.

Study Details

Study Typeinterventional
Allocation--
Masking--
Primary Purpose--
CountriesUnited States

Timeline

Phase 2CompletedFinished
20192020202120222023202420252026
First PostedJul 3, 2018
Enrollment StartAug 23, 2019
Primary CompletionJan 15, 2025
Study CompletionMar 30, 2025
TodayJul 2, 2026
Enrollment to primary: 5.4 yearsPosted 8.0 years ago

Interventions

Testosterone Undecanoatedrug

administered through injections by study staff

hybrid exercisebehavioral

hybrid exercise: functional electrical stimulation of lower extremity with leg cycling (FES-LC) and arm ergometry, supervised for two weeks and then home-based