CI

At a glance

ClinicalIndex Comparison Record
Early Ph 1Completed· 18 enrolled
Drug / intervention
Naringenin +1 moredietary
Likely dose
Not stated in record
Structured eligibility isn't available for this trial yet — see the full criteria in the Eligibility tab below.

Standardized by ClinicalIndex from the ClinicalTrials.gov record · verify against the source.

Search/NCT03582553
NCT03582553Early Ph 1Completed

Clinical Safety and Pharmacokinetic Evaluation of Naringenin: Single Dose Escalation Randomized Double Blind Controlled Trial

Pennington Biomedical Research Center·interventional·Posted Jul 11, 2018·Updated Jan 18, 2020

In Brief

A Early Phase 1 clinical trial evaluating Naringenin and Placebo for Safety Issues and Pharmacokinetics. Completed, enrolled 18 participants across 1 site.

Detailed Summary

This study evaluates the safety of administering single ascending doses (150, 300, 600, and 900 mg) of a citrus extract of the flavonoid narigenin, and assesses the blood concentrations of naringenin following oral administration of the extract.

Study Details

Study Typeinterventional
Allocation--
Masking--
Primary Purpose--
CountriesUnited States

Timeline

Early Ph 1CompletedFinished
20192020202120222023202420252026
First PostedJul 11, 2018
Enrollment StartMay 25, 2018
Primary CompletionSep 28, 2018
TodayJul 2, 2026
Enrollment to primary: 4 monthsPosted 8.0 years ago

Interventions

Naringenindietary

An extract of Citrus Sinensis containing naringenin and its precursor naringin

Placeboother

Cellulose