CI

At a glance

ClinicalIndex Comparison Record
Phase 2Completed· 251 enrolled
Drug / intervention
AGN-241751 +1 moredrug
Likely dose
Not stated in record
Structured eligibility isn't available for this trial yet — see the full criteria in the Eligibility tab below.

Standardized by ClinicalIndex from the ClinicalTrials.gov record · verify against the source.

Search/NCT03586427
NCT03586427Phase 2Completed

A Double-Blind, Placebo-Controlled, Fixed-Dose Study of AGN-241751 in Adult Participants With Major Depressive Disorder

Syndeio Biosciences, Inc·interventional·Posted Jul 13, 2018·Updated Apr 27, 2026

In Brief

A Phase 2 clinical trial evaluating AGN-241751 and Placebo for Depressive Disorder, Major. Completed, enrolled 251 participants across 25 sites.

Detailed Summary

The purpose of this study is to evaluate the efficacy at 1 day post initial oral dose of zelquistinel (AGN-241751) compared with placebo in participants with Major Depressive Disorder (MDD).

Study Details

Study Typeinterventional
Allocation--
Masking--
Primary Purpose--
CountriesUnited States
Collaborators--

Timeline

Phase 2CompletedFinished
20192020202120222023202420252026
First PostedJul 13, 2018
Enrollment StartJun 13, 2018
Primary CompletionJul 22, 2019
Study CompletionAug 21, 2019
TodayJul 2, 2026
Enrollment to primary: 1.1 yearsPosted 8.0 years ago

Interventions

AGN-241751drug

AGN-241751 administered orally as a single tablet

Placebodrug

Placebo administered orally as a single tablet