CI

At a glance

ClinicalIndex Comparison Record
N/AActive· 1,000 enrolled / 1,000 target
Drug / intervention
Monthly cash gift payments of $333 +1 morebehavioral
Likely dose
Not stated in record
Structured eligibility isn't available for this trial yet — see the full criteria in the Eligibility tab below.

Standardized by ClinicalIndex from the ClinicalTrials.gov record · verify against the source.

Search/NCT03593356
NCT03593356N/AActiveHigh Momentum (10.2/mo)

Household Income and Child Development in the First Three Years of Life (Phase 1) Household Income and Child Development in the First Years of Life (Phase 2)

University of California, Irvine·interventional·Posted Jul 20, 2018·Updated Jun 2, 2026

In Brief

A clinical study evaluating Monthly cash gift payments of $333 and Monthly cash gift payments of $20 for Child Development and 2 related conditions. Active but no longer recruiting, targeting 1,000 participants across 1 site.

Signals

Enrolling ahead of pace

Detailed Summary

Recent advances in developmental neuroscience suggest that experiences early in life can have profound and enduring influences on the developing brain. Family economic resources shape the nature of many of these experiences, yet the extent to which they affect children's development is unknown. The project's team of neuroscientists, economists and developmental psychologists is seeking to fill important gaps in scientific knowledge about the role of economic resources in early development by evaluating the first U.S. randomized controlled trial to determine whether unconditional cash gift payments have a causal effect on the cognitive, socio-emotional and brain development of infants and toddlers in low-income U.S. families. Specifically, 1,000 mothers of infants with incomes below the federal poverty line from four diverse U.S. communities were recruited from post-partum wards and are receiving monthly cash gift payments by debit card for the first 76 months of the child's life. Parents in the experimental group and receiving $333 per month ($3,996 per year), whereas parents in the active comparator group are receiving a nominal monthly payment of $20. In order to understand the impacts of the added income on children's cognitive and behavioral development, the investigators are assessing treatment group differences at ages 4 (this lab assessment was postponed from age 3 to age 4 due to Covid-19), 6, and 8 in lab-administered measures of cognitive, language, and self-regulation development and maternal reports of socio-emotional development. A number of other maternal-reported child outcome measures were gathered at ages 1, 2 and 3. Brain circuitry may be sensitive to the effects of early experience even before early behavioral differences can be detected. In order to understand the impacts of added income on children's brain functioning at age 4, 6, and 8, the investigators will assess, during a lab visit, experimental/active comparator group differences in measures of brain activity (electroencephalography \[EEG\]). The targeted age for each data collection wave is around the child's birthday, i.e. at 12 months, 24 months, 36 months, 48 months, 72 months, and 96 months. To understand how family economic behavior, parenting, and parent stress and well-being change in response to income enhancement, the investigators will assess experimental/active comparator differences in family expenditures, food insecurity, housing and neighborhood quality, family routines and time use, parent stress, mental health and cognition, parenting practices, and child care and preschool arrangements. School readiness and outcomes are being assessed at ages 6 and 8. This study will thus provide the first definitive understanding of the extent to which income plays a causal role in determining early child cognitive, socio-emotional and brain development among low-income families.

Study Details

Timeline

N/AActive
2019202020212022202320242025202620272028
First PostedJul 20, 2018
Enrollment StartMay 9, 2018
Primary CompletionJul 31, 2027
Study CompletionAug 31, 2028
TodayJul 2, 2026
Enrollment to primary: 9.2 yearsPosted 8.0 years agoPrimary completion in 1.1 years

Arms & Interventions

Monthly cash gift payments of $333experimental

These subjects receive $333 each month for 76 months via debit card.

Behavioral: Monthly cash gift payments of $333
Monthly cash gift payments of $20active_comparator

These subjects receive $20 each month for 76 months via debit card.

Behavioral: Monthly cash gift payments of $20

Interventions

Monthly cash gift payments of $333behavioral

These subjects receive $333 each month for 76 months via debit card.

Monthly cash gift payments of $20behavioral

These subjects receive $20 each month for 76 months via debit card.