CI

At a glance

ClinicalIndex Comparison Record
N/ACompleted· 236 enrolled
Drug / intervention
Not specified
Likely dose
Not stated in record
Structured eligibility isn't available for this trial yet — see the full criteria in the Eligibility tab below.

Standardized by ClinicalIndex from the ClinicalTrials.gov record · verify against the source.

Search/NCT03597438
NCT03597438N/ACompleted

Mitochondrial Targeted Biofuels as Countermeasures Against Chemical Threats

Children's Hospital of Philadelphia·observational·Posted Jul 24, 2018·Updated Feb 23, 2024

In Brief

An observational study for Mitochondrial Alteration. Completed, enrolled 236 participants across 1 site.

Detailed Summary

The purpose of the study is to determine in vitro effects on mitochondrial function of selected chemical agents in human cells, and assess the capability of a cell-permeable succinate prodrug to attenuate toxic effects The project aims at repurposing this recent pharmaceutical discovery, currently being developed for treatment of toxic exposure, for an expanded indication to treat chemically induced mitochondrial toxicity.

Study Details

Study Typeobservational
Allocation--
Masking--
Primary Purpose--
CountriesUnited States

Timeline

N/ACompletedFinished
20192020202120222023202420252026
First PostedJul 24, 2018
Enrollment StartMay 7, 2018
Primary CompletionApr 18, 2023
Study CompletionFeb 22, 2024
TodayJul 2, 2026
Enrollment to primary: 4.9 yearsPosted 7.9 years ago