At a glance
ClinicalIndex Comparison RecordPhase 2Completed· 84 enrolled
Drug / intervention
Melatonindrug
Likely dose
Not stated in record
Structured eligibility isn't available for this trial yet — see the full criteria in the Eligibility tab below.
Standardized by ClinicalIndex from the ClinicalTrials.gov record · verify against the source.
CHOCOlate MeLatonin for AdolescenT MigrainE: The CHOCOLATE Study
In Brief
A Phase 2 clinical trial evaluating Melatonin for Migraine. Completed, enrolled 84 participants across 1 site.
Detailed Summary
Existing treatments for acute migraine are not effective for all children and adolescents, and can cause side effects. Investigator propose a dose-finding study of melatonin for acute migraine treatment in children and adolescents to determine the best dose to bring forward in a future fully-powered efficacy trial.
Study Details
Study Typeinterventional
Allocation--
Masking--
Primary Purpose--
ConditionsMigraine
CountriesUnited States
Collaborators--
Timeline
Phase 2CompletedFinished
201820192020202120222023202420252026
Enrollment StartSep 2017
First PostedJul 2018
Primary CompletionDec 2019
TodayJul 2026
First PostedJul 24, 2018
Enrollment StartSep 25, 2017
Primary CompletionDec 1, 2019
TodayJul 2, 2026
Enrollment to primary: 2.2 yearsPosted 7.9 years ago
Interventions
Melatonindrug
melatonin