At a glance
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Aortic Valve-sparing Root Replacement Operation Versus Bentall Operation - Early and Midterm Outcomes
In Brief
A clinical study evaluating Aortic valve sparing operation and Bentall operation for Aortic Root Aneurysm and Aortic Root Dissection. Completed, enrolled 122 participants across 1 site.
Detailed Summary
This study was designed to evaluate the hypothesis that the operative and midterm results of valve-sparing aortic root replacement are equivalent to those of the Bentall. Objective 1: Evaluate short-term (one-to-six months) and mid-term (six-to-forty-eight months) results of aortic valve-sparing procedures. Objective 2: Compare the results of aortic valve-sparing procedures with the group of patients undergoing Bentall procedures during the same period. Objective 3: Assess outcomes of both procedures through evaluation of postoperative: A) primary outcome measures: 1. Intraoperative or intrahospital death. 2. Reexploration for bleeding. 3. Reoperation rate. 4. Grade of aortic valve regurgitation (0-4). B)secondary outcome measures: 1. Grade of aortic valve regurgitation (0-4). 2. Mean gradient on the aortic valve(mmHg). 3. Thromboembolism / bleeding. 4. Prosthetic/native valve endocarditis. 5. 2-year mortality
Study Details
Timeline
Interventions
Aortic valve sparing instead of replacement during aortic root replacement
Aortic root replacement with replacement of aortic valve