CI

At a glance

ClinicalIndex Comparison Record
Phase 4Completed· 75 enrolled
Drug / intervention
Lacosamide - conventional titration +2 moredrug
Likely dose
Lacosamide - conventional titration 50 mgfrom record
Structured eligibility isn't available for this trial yet — see the full criteria in the Eligibility tab below.

Standardized by ClinicalIndex from the ClinicalTrials.gov record · verify against the source.

Search/NCT03607851
NCT03607851Phase 4Completed
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Efficacy and Safety of Rapid Titration Protocols of Lacosamide: An Exploratory Study

Seoul National University Hospital·interventional·Posted Jul 31, 2018·Updated Feb 18, 2020

In Brief

A Phase 4 clinical trial evaluating Lacosamide - conventional titration, Lacosamide - rapid titration 1, and 1 other intervention for Focal Epilepsy. Completed, enrolled 75 participants across 1 site.

Detailed Summary

Three different dose titration schedules are tested to find a way to reduce the titration period of lacosamide

Study Details

Study Typeinterventional
Allocation--
Masking--
Primary Purpose--
ConditionsFocal Epilepsy
CountriesSouth Korea
CollaboratorsDongsan Medical Center, Konkuk University

Timeline

Phase 4CompletedFinished
20192020202120222023202420252026
First PostedJul 31, 2018
Enrollment StartAug 3, 2018
Primary CompletionJun 7, 2019
TodayJul 2, 2026
Enrollment to primary: 10 monthsPosted 7.9 years ago

Interventions

Lacosamide - conventional titrationdrug

Administration of lacosamide by the following schedule, Initial: 50 mg PO BID Increase dose at weekly intervals by 50 mg PO BID; up to 200 mg BID

Lacosamide - rapid titration 1drug

Administration of lacosamide by the following schedule, Initial: 100 mg PO BID Increase dose to 200 mg BID after one week

Lacosamide - rapid titration 2drug

Administration of lacosamide by the following schedule, Initial: 50 mg PO BID Increase dose every two days by 50 mg PO BID; up to 200 mg BID