CI

At a glance

ClinicalIndex Comparison Record
N/AActive· 155 enrolled
Drug / intervention
MILD Procedure +1 moredevice
Likely dose
Not stated in record
Structured eligibility isn't available for this trial yet — see the full criteria in the Eligibility tab below.

Standardized by ClinicalIndex from the ClinicalTrials.gov record · verify against the source.

Search/NCT03610737
NCT03610737N/AActive

A Multi-center, Randomized Controlled Study of the Vertos MILD Procedure With Conventional Medical Management Versus Conventional Medical Management Alone in the Treatment of Lumbar Spinal Stenosis.

Vertos Medical, Inc.·interventional·Posted Aug 1, 2018·Updated Oct 2, 2024

In Brief

A clinical study evaluating MILD Procedure and Conventional Medical Management (CMM) for Spinal Stenosis, Lumbar Region, With Neurogenic Claudication. Active but no longer recruiting, targeting 155 participants across 18 sites.

Detailed Summary

Prospective, multicenter, randomized controlled clinical study examining functional improvement in lumbar spinal stenosis (LSS) patients with neurogenic claudication who are treated with the MILD procedure plus conventional medical management (CMM) compared to those treated with CMM alone, as the control. Subjects in the control group are able to crossover and receive MILD after completion of 12-month follow-up. The study will provide objective functional improvement data for patients treated with the mild Procedure as first-line therapy in a real-world setting.

Study Details

Study Typeinterventional
Allocation--
Masking--
Primary Purpose--
CountriesUnited States
Collaborators--

Timeline

N/AActiveOverdue
20192020202120222023202420252026
First PostedAug 1, 2018
Enrollment StartAug 2, 2018
Primary CompletionMay 30, 2021
Study CompletionApr 30, 2025
TodayJul 2, 2026
Enrollment to primary: 2.8 yearsPosted 7.9 years ago

Interventions

MILD Proceduredevice

The percutaneous procedure is performed under fluoroscopic guidance to effect a lumbar decompression with minimal surrounding tissue and bone disruption. The mild® Device Kit is utilized to access, capture and remove bone and tissue. Other Name: MILD lumbar decompression

Conventional Medical Management (CMM)other

CMM can include physical therapy, home exercise, pain medication, epidural steroid injections, nerve blocks, and other lumbar steroid injections.