At a glance
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A Randomized Comparison Between Perineural Dexamethasone and Perineural Dexmedetomidine as Adjuvants for Ultrasound-Guided Infraclavicular Blocks
In Brief
A clinical study evaluating Dexamethasone and Dexmedetomidine for Pain, Postoperative and 2 related conditions. Completed, enrolled 120 participants across 1 site.
Detailed Summary
When used as perineural (PN) adjuvants to local anesthetics (LAs), dexamethasone (DX) and dexmedetomidine (DXD) have been well documented to prolong the duration of peripheral nerve blocks. These drugs have important differences in terms of cost and safety profiles. This randomized controlled trial (RCT) will compare PN DX and PN DXD for ultrasound-guided infraclavicular brachial plexus blocks (ICBs). Since analgesic and sensory duration can be influenced by factors different to block, motor block duration is the main outcome. The protocol is designed as an equivalency trial and hypothesize that both drugs result in similar durations. The equivalency margin is set at 3 hrs.
Study Details
Timeline
Interventions
Dexamethasone as perineural local anesthetic adjuvant
Dexmedetomidine as perineural local anesthetic adjuvant