At a glance
ClinicalIndex Comparison RecordStandardized by ClinicalIndex from the ClinicalTrials.gov record · verify against the source.
Topical Products to Treat Xerostomia in Primary Sjögren's Syndrome: a Double-blind Clinical Trial
In Brief
A clinical study evaluating Mouthwash treatment, Toothpaste treatment, and 2 other interventions for Xerostomia and Sjogren's Syndrome. Completed, enrolled 28 participants.
Detailed Summary
Objectives: To assess the effects of topical dry mouth products (toothpaste and mouthwash) containing olive oil, parsley oil, provitamin B5, allantoin, betaine and xylitol in Primary Sjögren's syndrome patients with xerostomia. Subjects and Methods: A double-blinded, placebo-controlled, randomized design where participants were randomly assigned at baseline test or placebo products. Participants used the products 3 times/day/28 days. The investigators used Visual Analog Scale for xerostomia and Oral Health Impact Profile-14, baseline and after treatment, to assess the possible improvement.
Study Details
Timeline
Interventions
60 seconds after meals (3 times/day) during 28 days
3 minutes after the mouthwash (3 times/day) during 28 days
60 seconds after meals (3 times/day) during 28 days
3 minutes after the mouthwash (3 times/day) during 28 days