At a glance
ClinicalIndex Comparison RecordEarly Ph 1Completed· 20 enrolled
Drug / intervention
Oxycodone Medication First +1 moredrug
Likely dose
Oxycodone Medication First 15mgfrom record
Structured eligibility isn't available for this trial yet — see the full criteria in the Eligibility tab below.
Standardized by ClinicalIndex from the ClinicalTrials.gov record · verify against the source.
Influence of Medication on Functional Connectivity
In Brief
A Early Phase 1 clinical trial evaluating Oxycodone Medication First and Placebo First for Prescription Drug Abuse (Not Dependent). Completed, enrolled 20 participants across 1 site.
Detailed Summary
This study will assess the effects of acute low-dose opioid administration on functional neuroimaging measures in healthy individuals
Study Details
Study Typeinterventional
Allocation--
Masking--
Primary Purpose--
ConditionsPrescription Drug Abuse (Not Dependent)
CountriesUnited States
CollaboratorsNational Institute on Drug Abuse (NIDA)
Timeline
Early Ph 1CompletedFinished
20192020202120222023202420252026
First PostedAug 2018
Enrollment StartOct 2018
Primary CompletionJun 2022
TodayJul 2026
First PostedAug 2, 2018
Enrollment StartOct 30, 2018
Primary CompletionJun 2, 2022
TodayJul 2, 2026
Enrollment to primary: 3.6 yearsPosted 7.9 years ago
Interventions
Oxycodone Medication Firstdrug
Participants will be given 15mg oxycodone one hour before fMRI scan. After at least 1 week wash out participants will be given placebo one hour before fMRI scan.
Placebo Firstdrug
Participants will be given placebo one hour before fMRI scan. After at least 1 week wash out participants will be given 15mg oxycodone one hour before fMRI scan.