CI

At a glance

ClinicalIndex Comparison Record
Phase 3Completed· 212 enrolled
Drug / intervention
ZYN002 - Cannabidiol Transdermal Gel +1 moredrug
Likely dose
Not stated in record
Structured eligibility isn't available for this trial yet — see the full criteria in the Eligibility tab below.

Standardized by ClinicalIndex from the ClinicalTrials.gov record · verify against the source.

Search/NCT03614663
NCT03614663Phase 3Completed

A Randomized, Double-Blind, Placebo-Controlled Multiple-Center, Efficacy and Safety Study of ZYN002 Administered as a Transdermal Gel to Children and Adolescents With Fragile X Syndrome

Zynerba Pharmaceuticals, Inc.·interventional·Posted Aug 3, 2018·Updated Jul 6, 2022

In Brief

A Phase 3 clinical trial evaluating ZYN002 - Cannabidiol Transdermal Gel and Placebo Transdermal Gel for Fragile X Syndrome. Completed, enrolled 212 participants across 21 sites in 3 countries.

Detailed Summary

This trial will evaluate the efficacy and safety of ZYN002, a clear cannabidiol gel that can be applied to the skin (called transdermal application) twice a day for the treatment of behavioral symptoms of Fragile X Syndrome (FXS). Eligible participants will then participate in up to a 14 week treatment period, where all participants will receive placebo or active study drug. Patients ages 3 to \< 18 years, will be eligible to participate.

Study Details

Study Typeinterventional
Allocation--
Masking--
Primary Purpose--
CountriesAustralia, New Zealand, United States
Collaborators--

Timeline

Phase 3CompletedFinished
20192020202120222023202420252026
First PostedAug 3, 2018
Enrollment StartJun 12, 2018
Primary CompletionJun 14, 2020
TodayJul 2, 2026
Enrollment to primary: 2.0 yearsPosted 7.9 years ago

Interventions

ZYN002 - Cannabidiol Transdermal Geldrug

Pharmaceutically manufactured. Cannabidiol formulated as a clear gel (transdermal delivery)

Placebo Transdermal Gelother

Placebo formulated as a clear gel (transdermal delivery)