CI

At a glance

ClinicalIndex Comparison Record
N/ACompleted· 140 enrolled
Drug / intervention
High Intensity Interval Training (HIIT) +2 moreother
Likely dose
Not stated in record
Structured eligibility isn't available for this trial yet — see the full criteria in the Eligibility tab below.

Standardized by ClinicalIndex from the ClinicalTrials.gov record · verify against the source.

Search/NCT03617185
NCT03617185N/ACompleted

The Effect of High Intensity Interval Training and Surgical Weight Loss on Distal Symmetric Polyneuropathy Outcomes

University of Michigan·interventional·Posted Aug 6, 2018·Updated Feb 24, 2026

In Brief

A clinical study evaluating High Intensity Interval Training (HIIT), Routine Exercise, and 1 other intervention for Polyneuropathies and 2 related conditions. Completed, enrolled 140 participants across 1 site.

Detailed Summary

The purpose of this research study is to evaluate how exercise and surgical weight loss affect how likely an individual is to develop peripheral neuropathy and other neurologic complications.

Study Details

Study Typeinterventional
Allocation--
Masking--
Primary Purpose--
CountriesUnited States

Timeline

N/ACompletedFinished
20192020202120222023202420252026
First PostedAug 6, 2018
Enrollment StartJul 27, 2018
Primary CompletionAug 1, 2024
TodayJul 2, 2026
Enrollment to primary: 6.0 yearsPosted 7.9 years ago

Interventions

High Intensity Interval Training (HIIT)other

Patients will complete a HIIT training protocol of a total of 10 x 1 min intervals at 90% heart rate (HR) max. They will continue this training protocol, 3 sessions a week (2 supervised and 1 unsupervised), for 24 months.

Routine Exerciseother

Patients will receive counseling regarding exercise as a routine part of their participation in the bariatric surgery clinic. Specifically, they are counseled to participate in 60 min of aerobic exercise daily in addition to 2-3 non-consecutive days of strength training workouts every wk. Patients are encouraged to contact the bariatric conditioning program, obtain a gym membership, purchase exercise equipment, join a walking group, and/or sign up for fitness classes (employer or city parks and recreation).

Bariatric surgeryprocedure

Patients will undergo bariatric surgery as part of their routine care