CI

At a glance

ClinicalIndex Comparison Record
Phase 2Completed· 22 enrolled
Drug / intervention
Neuromuscular magnetic stimulation (NMMS)device
Likely dose
Not stated in record
Structured eligibility isn't available for this trial yet — see the full criteria in the Eligibility tab below.

Standardized by ClinicalIndex from the ClinicalTrials.gov record · verify against the source.

Search/NCT03618966
NCT03618966Phase 2Completed
CompareCT.gov

Neuromuscular Magnetic Stimulation Counteracts Muscle Decline in ALS Patients

University of Roma La Sapienza·interventional·Posted Aug 7, 2018·Updated Aug 7, 2018

In Brief

A Phase 2 clinical trial evaluating Neuromuscular magnetic stimulation (NMMS) for Amyotrophic Lateral Sclerosis. Completed, enrolled 22 participants.

Detailed Summary

Aim of the study is to verify whether neuromuscular magnetic stimulation can improve muscle function in spinal-onset Amyotrophic Lateral Sclerosis (ALS) patients.

Study Details

Study Typeinterventional
Allocation--
Masking--
Primary Purpose--
ConditionsAmyotrophic Lateral Sclerosis
Countries--
Collaborators--

Timeline

Phase 2CompletedFinished
201520162017201820192020202120222023202420252026
First PostedAug 7, 2018
Enrollment StartNov 1, 2014
Primary CompletionMay 1, 2016
Study CompletionNov 1, 2017
TodayJul 2, 2026
Enrollment to primary: 1.5 yearsPosted 7.9 years ago

Interventions

Neuromuscular magnetic stimulation (NMMS)device

It is a non-invasive, stimulation technique that does not induce high-intensity cutaneous electric fields and does not activate skin nociceptors, thus resulting in a painless and better-tolerated procedure. rNMMS is delivered through a high-frequency magnetic stimulator connected to a conventional circular cooled coil. Magnetic stimulator is placed above the flexor muscles of the forearm. rNMMS is delivered at a 5-Hz frequency and with a 100% stimulation intensity of 100% of the maximum intensity in 140 trains of 50 stimuli. sNMMS is delivered with a sham coil producing similar acoustic sensations and mechanical skin perceptions.