CI

At a glance

ClinicalIndex Comparison Record
Phase 3Completed· 51 enrolled
Drug / intervention
Levoketoconazoledrug
Likely dose
Levoketoconazole 1200 mgfrom record
Structured eligibility isn't available for this trial yet — see the full criteria in the Eligibility tab below.

Standardized by ClinicalIndex from the ClinicalTrials.gov record · verify against the source.

Search/NCT03621280
NCT03621280Phase 3Completed

An Open-label Extension Study of Levoketoconazole (2S,4R-ketoconazole) in the Treatment of Endogenous Cushing's Syndrome

Cortendo AB·interventional·Posted Aug 8, 2018·Updated Jun 19, 2025

In Brief

A Phase 3 clinical trial evaluating Levoketoconazole for Cushing Syndrome and Cushing Disease. Completed, enrolled 51 participants across 30 sites in 11 countries.

Detailed Summary

This is a long-term, open-label extension study of levoketoconazole in participants with endogenous Cushing's Syndrome.

Study Details

Study Typeinterventional
Allocation--
Masking--
Primary Purpose--
CountriesBulgaria, France, Greece, Hungary, Israel, Italy, Netherlands, Poland, Romania, Spain, United States
Collaborators--

Timeline

Phase 3CompletedFinished
20192020202120222023202420252026
First PostedAug 8, 2018
Enrollment StartJan 7, 2019
Primary CompletionDec 31, 2022
TodayJul 2, 2026
Enrollment to primary: 4.0 yearsPosted 7.9 years ago

Interventions

Levoketoconazoledrug

Levoketoconazole up to 1200 mg daily