CI

At a glance

ClinicalIndex Comparison Record
N/ACompleted· 44 enrolled
Drug / intervention
Power training combined with interval treadmill training +1 morebehavioral
Likely dose
Not stated in record
Structured eligibility isn't available for this trial yet — see the full criteria in the Eligibility tab below.

Standardized by ClinicalIndex from the ClinicalTrials.gov record · verify against the source.

Search/NCT03625570
NCT03625570N/ACompleted

Power Training Combined With Interval Treadmill Training to Improve Walking Activity in Cerebral Palsy (PT³)

Louisiana State University Health Sciences Center in New Orleans·interventional·Posted Aug 10, 2018·Updated Dec 13, 2024

In Brief

A clinical study evaluating Power training combined with interval treadmill training and Strength training combined with traditional treadmill training for Cerebral Palsy and 2 related conditions. Completed, enrolled 44 participants across 2 sites.

Detailed Summary

Ambulatory children with cerebral palsy (CP) experience walking limitations which negatively influence their ability to physically participate in day to day life. The investigators propose that impaired muscle power generation is the key limiting factor affecting walking activity and participation. This proposal represents a combined approach where participants undergo resistance training for muscle power generation in combination with locomotor treadmill training that is based on typical pediatric walking and activity patterns rather than adult protocols, which are endurance or time-based. Therefore, the primary objective of this randomized controlled trial is to determine the effect of lower extremity Power Training combined with interval Treadmill Training (PT³) on functional walking capacity and community-based activity and participation in children with CP. We hypothesize that remediating the most pronounced muscle performance impairment (i.e., muscle power) with power training combined with a task- specific approach to walking that is developmentally appropriate will have a significant effect on walking capacity and performance.

Study Details

Timeline

N/ACompletedFinished
20192020202120222023202420252026
First PostedAug 10, 2018
Enrollment StartApr 15, 2019
Primary CompletionOct 4, 2023
Study CompletionNov 10, 2023
TodayJul 2, 2026
Enrollment to primary: 4.5 yearsPosted 7.9 years ago

Interventions

Power training combined with interval treadmill trainingbehavioral

Training will consist of unilateral and bilateral leg presses, targeting the quadriceps, hip extensors, and plantarflexors according to resistance training guidelines for muscle power training. The interval treadmill training portion will include short-bursts (30 seconds) of high speed walking intervals alternating with 30 seconds of low to moderate speed walking for a total of 30 minutes. Participants will train 3 x per week for 8 weeks. Total duration of each session will be approximately 1 hour.

Strength training combined with traditional treadmill trainingbehavioral

Training will consist of unilateral and bilateral leg presses, targeting the quadriceps, hip extensors, and plantarflexors following the dosing and resistance training guidelines for muscle strength. Traditional treadmill training will consist of walking at steady-state speeds for 30 minutes. Participants will train 3 x per week for 8 weeks. Total duration of each session will be approximately 1 hour.