CI

At a glance

ClinicalIndex Comparison Record
N/ACompleted· 300 enrolled
Drug / intervention
Norepinephrine Bolus +3 moredrug
Likely dose
Norepinephrine Bolus 6 µgfrom record
Structured eligibility isn't available for this trial yet — see the full criteria in the Eligibility tab below.

Standardized by ClinicalIndex from the ClinicalTrials.gov record · verify against the source.

Search/NCT03626454
NCT03626454N/ACompleted

Efficacy and Safety of Prophylactic Norepinephrine Addition in Prevention of Hypotension During Spinal Anesthesia for Caesarean Delivery: A Randomized Trial

Fayoum University Hospital·interventional·Posted Aug 13, 2018·Updated Nov 26, 2024

In Brief

A clinical study evaluating Norepinephrine Bolus, Norepinephrine infusion, and 2 other interventions for Hypotension Drug-Induced. Completed, enrolled 300 participants across 1 site.

Detailed Summary

The objective is to compare efficacy of prophylactic norepinephrine bolus versus Infusion in prevention of hypotension which occurs frequently after spinal anesthesia for caesarean section. The authors hypothesize that prophylactic norepinephrine bolus is as effective as infusion in Prevention of hypotension after spinal anesthesia in caesarean section

Study Details

Study Typeinterventional
Allocation--
Masking--
Primary Purpose--
CountriesEgypt
Collaborators--

Timeline

N/ACompletedFinished
20192020202120222023202420252026
First PostedAug 13, 2018
Enrollment StartOct 16, 2020
Primary CompletionJan 1, 2024
Study CompletionFeb 1, 2024
TodayJul 2, 2026
Enrollment to primary: 3.2 yearsPosted 7.9 years ago

Interventions

Norepinephrine Bolusdrug

'Norepinephrine Bitartarte' bolus of 6 µg/mL for 30 seconds immediately after intrathecal injection

Norepinephrine infusiondrug

an infusion of 6 µg/mL norepinephrine that was started at 6 µg/kg/h immediately after intrathecal injection

Normal Saline Flush, 0.9% Injectable Solutiondrug

10 ml normal saline in syringe for bolus for 30 seconds immediately after intrathecal injection

Normal Saline 0.9% Infusion Solutiondrug

50 ml syringe with normal saline infuse at a rate 1ml/kg/h immediately after intrathecal injection