CI

At a glance

ClinicalIndex Comparison Record
Phase 3Completed· 173 enrolled
Drug / intervention
Baloxavir Marboxil +1 moredrug
Likely dose
Not stated in record
Structured eligibility isn't available for this trial yet — see the full criteria in the Eligibility tab below.

Standardized by ClinicalIndex from the ClinicalTrials.gov record · verify against the source.

Search/NCT03629184
NCT03629184Phase 3Completed

A Multicenter, Randomized, Double-Blind, Active (Oseltamivir)-Controlled Study to Assess the Safety, Pharmacokinetics, and Efficacy of Baloxavir Marboxil in Otherwise Healthy Pediatric Patients 1 to <12 Years of Age With Influenza-Like Symptoms

Hoffmann-La Roche·interventional·Posted Aug 14, 2018·Updated Apr 29, 2020

In Brief

A Phase 3 clinical trial evaluating Baloxavir Marboxil and Oseltamivir for Influenza. Completed, enrolled 173 participants across 37 sites in 7 countries.

Detailed Summary

This study will evaluate the safety, pharmacokinetics, and efficacy of baloxavir marboxil compared with oseltamivir in a single influenza episode in otherwise healthy pediatric participants (i.e., 1 to \<12 years of age) with influenza-like symptoms.

Study Details

Study Typeinterventional
Allocation--
Masking--
Primary Purpose--
ConditionsInfluenza
CountriesCosta Rica, Israel, Mexico, Poland, Russia, Spain, United States
Collaborators--

Timeline

Phase 3CompletedFinished
20192020202120222023202420252026
First PostedAug 14, 2018
Enrollment StartNov 20, 2018
Primary CompletionApr 3, 2019
TodayJul 2, 2026
Enrollment to primary: 4 monthsPosted 7.9 years ago

Interventions

Baloxavir Marboxildrug

Baloxavir marboxil will be administered as oral suspension in a single dose on Day 1. Oseltamivir matching placebo will also be administered as oral suspension twice daily (BID) for 5 days.

Oseltamivirdrug

Oseltamivir will be administered as oral suspension BID for 5 days. Participants receiving oseltamivir will also receive baloxavir marboxil matching placebo as oral suspension, single dose on Day 1.