CI

At a glance

ClinicalIndex Comparison Record
Phase 4Completed· 102 enrolled
Drug / intervention
Ibuprofen 600 mg +1 moredrug
Likely dose
Ibuprofen 600 mgfrom record
Structured eligibility isn't available for this trial yet — see the full criteria in the Eligibility tab below.

Standardized by ClinicalIndex from the ClinicalTrials.gov record · verify against the source.

Search/NCT03631433
NCT03631433Phase 4Completed
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An Evaluation of Postoperative Pain Using Ibuprofen Versus Ibuprofen/Acetaminophen in Patients With Symptomatic Irreversible Pulpitis and Symptomatic Apical Periodontitis

Ohio State University·interventional·Posted Aug 15, 2018·Updated May 4, 2021

In Brief

A Phase 4 clinical trial evaluating Ibuprofen 600 mg and ibuprofen 600 mg and acetaminophen 650 mg for Pain, Postoperative. Completed, enrolled 102 participants.

Detailed Summary

Aim: The purpose of this study was to compare ibuprofen versus an ibuprofen/acetaminophen combination for postoperative pain control in patients requiring root canal treatment with a tooth that is painful to cold and biting. Methodology: Following regular root canal treatment, patients randomly received identical appearing tablets of 600 mg ibuprofen or 600 mg ibuprofen/650 mg acetaminophen to be taken every 6 hours as needed for pain. A 4-day diary was used to record pain and medication use.

Study Details

Study Typeinterventional
Allocation--
Masking--
Primary Purpose--
ConditionsPain, Postoperative
Countries--
Collaborators--

Timeline

Phase 4CompletedFinished
20162017201820192020202120222023202420252026
First PostedAug 15, 2018
Enrollment StartFeb 10, 2016
Primary CompletionMay 1, 2017
Study CompletionJul 17, 2017
TodayJul 2, 2026
Enrollment to primary: 1.2 yearsPosted 7.9 years ago

Interventions

Ibuprofen 600 mgdrug

identical appearing tablets containing 600 mg of ibuprofen

ibuprofen 600 mg and acetaminophen 650 mgdrug

identical appearing tablets of the combination of ibuprofen and acetaminophen