CI

At a glance

ClinicalIndex Comparison Record
N/ACompleted· 42 enrolled
Drug / intervention
retinyl palmitatedietary
Likely dose
Not stated in record
Structured eligibility isn't available for this trial yet — see the full criteria in the Eligibility tab below.

Standardized by ClinicalIndex from the ClinicalTrials.gov record · verify against the source.

Search/NCT03632876
NCT03632876N/ACompleted
CompareCT.gov

Vitamin A in Sickle Cell Disease: Improving Sub-optimal Status With Supplementation

Children's Hospital of Philadelphia·interventional·Posted Aug 16, 2018·Updated Aug 16, 2018

In Brief

A clinical study evaluating retinyl palmitate for Sickle Cell Anemia in Children and Vitamin A Deficiency in Children. Completed, enrolled 42 participants across 1 site.

Detailed Summary

This study establishes the safety and efficacy of vit A supplementation doses (3000 and 6000 IU/d) over 8 weeks in children with SCD-SS, ages 9 and older and test the impact of vit A supplementation on key functional and clinical outcomes. Additionally, vitamin A status is assessed in healthy children ages 9 and older to compare to subjects with SCD-SS.

Study Details

Study Typeinterventional
Allocation--
Masking--
Primary Purpose--
ConditionsSickle Cell Anemia in Children, Vitamin A Deficiency in Children
CountriesUnited States
CollaboratorsPenn State University, Newcastle University

Timeline

N/ACompletedFinished
20162017201820192020202120222023202420252026
First PostedAug 16, 2018
Enrollment StartOct 2, 2015
Primary CompletionSep 30, 2016
TodayJul 2, 2026
Enrollment to primary: 12 monthsPosted 7.9 years ago

Interventions

retinyl palmitatedietary

The intervention is a daily vitamin A supplement.