CI

At a glance

ClinicalIndex Comparison Record
Phase 1Completed· 130 enrolled
Drug / intervention
Nicotine +1 moredrug
Likely dose
Nicotine 18 mgfrom record
Structured eligibility isn't available for this trial yet — see the full criteria in the Eligibility tab below.

Standardized by ClinicalIndex from the ClinicalTrials.gov record · verify against the source.

Search/NCT03635333
NCT03635333Phase 1Completed
CompareCT.gov

Effects of E-Cigarette Flavors on Adults

Yale University·interventional·Posted Aug 17, 2018·Updated Dec 19, 2025

In Brief

A Phase 1 clinical trial evaluating Nicotine and Flavor for Nicotine Use Disorder. Completed, enrolled 130 participants across 1 site.

Detailed Summary

This study looks at the effects of flavors when administered with nicotine in e-cigarettes in younger and older adult cigarette smokers.

Study Details

Study Typeinterventional
Allocation--
Masking--
Primary Purpose--
ConditionsNicotine Use Disorder
CountriesUnited States
CollaboratorsNational Institute on Drug Abuse (NIDA)

Timeline

Phase 1CompletedFinished
20192020202120222023202420252026
First PostedAug 17, 2018
Enrollment StartMay 14, 2019
Primary CompletionJul 12, 2023
TodayJul 2, 2026
Enrollment to primary: 4.2 yearsPosted 7.9 years ago

Interventions

Nicotinedrug

Nicotine level (6 or 18 mg)

Flavordrug

Flavor of e-juice (tobacco, menthol, cherry, vanilla)