At a glance
ClinicalIndex Comparison RecordStandardized by ClinicalIndex from the ClinicalTrials.gov record · verify against the source.
Vasopressin and Methylprednisolone for In-Hospital Cardiac Arrest - A Randomized, Double-Blind, Placebo-Controlled Trial
In Brief
A Phase 3 clinical trial evaluating Vasopressin, Arginine, Methylprednisolone, and 1 other intervention for Heart Arrest. Completed, enrolled 501 participants across 10 sites.
Detailed Summary
This is an investigator-initiated, multicenter, randomized, placebo-controlled, parallel group, double-blind, superiority trial of vasopressin and methylprednisolone during adult in-hospital cardiac arrest. There will be ten enrolling sites in Denmark. 492 adult patients with in-hospital cardiac arrest receiving at least one dose of adrenaline will be enrolled. The primary outcome is return of spontaneous circulation and key secondary outcomes include survival at 30 days and survival at 30 days with a favorable neurological outcome.
Study Details
Timeline
Interventions
20 IE of vasopressin per dose for a maximum of four doses (80 IU)
40 mg methylprednisolone once
Placebo