CI

At a glance

ClinicalIndex Comparison Record
N/ACompleted· 182 enrolled
Drug / intervention
CNVprocedure
Likely dose
Not stated in record
Structured eligibility isn't available for this trial yet — see the full criteria in the Eligibility tab below.

Standardized by ClinicalIndex from the ClinicalTrials.gov record · verify against the source.

Search/NCT03642574
NCT03642574N/ACompleted
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Cumulative Live Birth Rate With eSET After Preimplantation DNA Methylation Test (PIMT) in ART

Chen Zi-Jiang·interventional·Posted Aug 22, 2018·Updated Oct 4, 2022

In Brief

A clinical study evaluating CNV for DNA Methylation. Completed, enrolled 182 participants across 1 site.

Detailed Summary

The purpose of this clinical trial is to determine the safety and effect of methylation level of DNA methylation in embryos on the outcome of assisted reproductive technology (ART) during blastocyst embryo screening. Subjects with blastocysts on day 5-7 of embryo culture will be biopsied. A Freeze-all strategy and a single frozen blastocyst transfer will be performed till all study-specific embryos have been transferred. Then whole genome bisulfate sequencing will be performed on all cells that obtained from biopsy.

Study Details

Study Typeinterventional
Allocation--
Masking--
Primary Purpose--
ConditionsDNA Methylation
CountriesChina
CollaboratorsChinese Academy of Sciences

Timeline

N/ACompletedFinished
20192020202120222023202420252026
First PostedAug 22, 2018
Enrollment StartSep 5, 2018
Primary CompletionAug 28, 2021
Study CompletionJun 30, 2022
TodayJul 2, 2026
Enrollment to primary: 3.0 yearsPosted 7.9 years ago

Interventions

CNVprocedure

Embryo with euploid chromosome will transfer to uterus. The order of transfer is accroding to morphological grade.