At a glance
ClinicalIndex Comparison RecordStandardized by ClinicalIndex from the ClinicalTrials.gov record · verify against the source.
Randomized, Double-blind, Parallel Group, Single-center, Placebo-controlled Study to Evaluate Efficacy and Safety of Analgesic Combo in Prevention and Treatment of Post-surgical Dental Pain in Healthy Subjects
In Brief
A Phase 2 clinical trial evaluating Pre-Op pregabalin, Pre-Op Placebo 1, and 4 other interventions for Dental Pain. Completed, enrolled 115 participants across 1 site.
Detailed Summary
* Accessing the efficacy and safety of pregabalin when used alone and in combo with acetaminophen in a dental pain model. * To test whether pre-operative dose of pregabalin increases the time to significant post-operative pain (NRS ≥ 5), and hence time to first analgesia consumed post-operatively.
Study Details
Timeline
Interventions
Pre-op pregabalin will be administered 60 min prior to surgery.
Placebo 1 will be administered 60 min prior to surgery.
Post-op pregabalin will be administered Post-operatively.
Placebo 1 will be administered post-operatively.
Placebo 2 will be administered post-operatively.
Acetaminophen will be administered Post-operatively.