CI

At a glance

ClinicalIndex Comparison Record
N/ACompleted· 144 enrolled
Drug / intervention
Active HEPA Air Cleaner +2 moredevice
Likely dose
Not stated in record
Structured eligibility isn't available for this trial yet — see the full criteria in the Eligibility tab below.

Standardized by ClinicalIndex from the ClinicalTrials.gov record · verify against the source.

Search/NCT03658538
NCT03658538N/ACompleted

Motivational Interviewing and Air Cleaners for Smokers With COPD (MOVE COPD)

Johns Hopkins University·interventional·Posted Sep 5, 2018·Updated Sep 24, 2025

In Brief

A clinical study evaluating Active HEPA Air Cleaner, Motivational interviewing, and 1 other intervention for COPD, Chronic Obstructive Pulmonary Disease. Completed, enrolled 144 participants across 1 site.

Detailed Summary

COPD is characterized by lung injury and inflammation caused by noxious particles and gases, including those emanating from cigarette smoke and air pollution. Despite the clear detrimental impact of poor air quality on respiratory outcomes, regardless of smoking status, to investigators' knowledge, there are no studied environmental interventions targeting indoor air quality to improve respiratory health of smokers, thus ignoring a potential target for harm reduction. Investigators propose a randomized controlled intervention trial to test whether targeted reductions of multiple indoor pollutants (PM, SHS and NO2) in homes of smokers with COPD will improve respiratory outcomes. Investigators have chosen a potent, multimodal intervention (active air cleaners + Motivational intervention for SHS reduction) in order to maximize the opportunity to prove that there is a health benefit to active smokers with COPD from indoor air pollution reduction.

Study Details

Study Typeinterventional
Allocation--
Masking--
Primary Purpose--
CountriesUnited States

Timeline

N/ACompletedFinished
20192020202120222023202420252026
First PostedSep 5, 2018
Enrollment StartJun 3, 2019
Primary CompletionAug 15, 2024
Study CompletionNov 7, 2024
TodayJul 2, 2026
Enrollment to primary: 5.2 yearsPosted 7.8 years ago

Interventions

Active HEPA Air Cleanerdevice

The active treatment arm will receive two active air cleaners with HEPA and carbon filters to support a home smoking ban and SHS reduction.

Motivational interviewingbehavioral

The active treatment arm will receive 4 sessions of phone based motivational interviewing to support a home smoking ban and SHS reduction (in addition to the smoking cessation counseling received by all study participants). The Control arm will receive only continued counseling for smoking cessation.

Sham Air Cleanerdevice

The Control arm will receive sham air cleaners