CI

At a glance

ClinicalIndex Comparison Record
Phase 3Completed· 854 enrolled
Drug / intervention
CNTX-4975-05 +3 moredrug
Likely dose
Lidocaine without epinephrine 15 mLfrom record
Structured eligibility isn't available for this trial yet — see the full criteria in the Eligibility tab below.

Standardized by ClinicalIndex from the ClinicalTrials.gov record · verify against the source.

Search/NCT03661996
NCT03661996Phase 3Completed
CompareCT.gov

An Open-label, 8-Week Study to Compare the Comfort and Ease of Use of Five Different Treatment Regimens for CNTX-4975-05 Intra-articular Injection in Subjects With Chronic, Moderate-to-Severe Osteoarthritis Knee Pain

Centrexion Therapeutics·interventional·Posted Sep 7, 2018·Updated Mar 9, 2022

In Brief

A Phase 3 clinical trial evaluating CNTX-4975-05, Lidocaine without epinephrine, and 2 other interventions for Knee Osteoarthritis. Completed, enrolled 854 participants across 28 sites.

Detailed Summary

An Open-label, 8-Week Study to Compare the Comfort and Ease of Use of Five Different Treatment Regimens for CNTX 4975-05 Intra-articular Injection in Subjects with Chronic, Moderate-to-Severe Osteoarthritis Knee Pain.

Study Details

Study Typeinterventional
Allocation--
Masking--
Primary Purpose--
ConditionsKnee Osteoarthritis
CountriesUnited States
Collaborators--

Timeline

Phase 3CompletedFinished
20192020202120222023202420252026
First PostedSep 7, 2018
Enrollment StartSep 18, 2018
Primary CompletionOct 22, 2019
TodayJul 2, 2026
Enrollment to primary: 1.1 yearsPosted 7.8 years ago

Interventions

CNTX-4975-05drug

Osteoarthritis (OA) intra-articular injection of CNTX-4975-05

Lidocaine without epinephrinedrug

15 mL lidocaine intra-articular injection

ElastoGeldevice

Cooling Device

Breg Ice Water Pumpdevice

Cooling Device