CI

At a glance

ClinicalIndex Comparison Record
N/ACompleted· 44 enrolled
Drug / intervention
Active transcranial Direct Current Stimulation +1 moreother
Likely dose
Not stated in record
Structured eligibility isn't available for this trial yet — see the full criteria in the Eligibility tab below.

Standardized by ClinicalIndex from the ClinicalTrials.gov record · verify against the source.

Search/NCT03666533
NCT03666533N/ACompleted

Transcranial Direct Current Stimulation for Post-stroke Gait Rehab

VA Office of Research and Development·interventional·Posted Sep 11, 2018·Updated Sep 16, 2025

In Brief

A clinical study evaluating Active transcranial Direct Current Stimulation and Sham transcranial Direct Current Stimulation for Stroke and Gait Impairment. Completed, enrolled 44 participants across 1 site.

Detailed Summary

Stroke affects upwards of 800,000 Americans every year and has an enormous impact on the well-being of the American Veteran population with 6,000 new stroke admissions every year. Many of these stroke survivors are living with walking disabilities. Gait problems result in inability to function independently, high risk of falls and poor quality of life. Unfortunately, current gait rehabilitation treatments are limited and many stroke survivors do not achieve full recovery. Therefore, it is critical to develop new approaches to enhance gait rehabilitation methods. The investigators propose to evaluate a brain stimulation treatment called transcranial Direct Current Stimulation (tDCS) that can be added to physical therapy. tDCS has been applied for arm rehabilitation after stroke with positive results, but gait-related investigations are lacking. The investigators will test whether simultaneous tDCS and gait training produces greater improvement in walking abilities than gait training alone. Adjunct tDCS therapy may improve outcomes, and reduce cost of both rehabilitation and post-stroke care.

Study Details

Study Typeinterventional
Allocation--
Masking--
Primary Purpose--
CountriesUnited States
Collaborators--

Timeline

N/ACompletedFinished
20192020202120222023202420252026
First PostedSep 11, 2018
Enrollment StartSep 13, 2018
Primary CompletionMar 29, 2024
TodayJul 2, 2026
Enrollment to primary: 5.5 yearsPosted 7.8 years ago

Interventions

Active transcranial Direct Current Stimulationother

Active tDCS is combined with gait therapy. Gait therapy includes gait task practice in Virtual Reality setting and overground gait therapy

Sham transcranial Direct Current Stimulationother

Sham tDCS is combined with gait therapy. Gait therapy includes gait task practice in Virtual Reality setting and overground gait therapy