At a glance
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The Influence of Autologous Platelet Concentrates on Human Keratinocyte Proliferation in Vitro and Wound Healing in Vivo
In Brief
A clinical study evaluating Platelet-Rich Plasma for Platelet-Rich Plasma and Wound Healing Delayed. Completed, enrolled 5 participants across 1 site.
Detailed Summary
Chronic soft tissues defects can extend into the fat layer or even deeper and can cause functional disadvantages. Split-thickness skin grafts (STSGs) used to cover these wounds have varying success rates. To improve wound healing in chronic wounds the authors have studied the application of autologous platelet concentrates in a human keratinocyte culture model in vitro and in a combination with surgical procedures in vivo as second line therapy in patients with initially failed wound closure.
Study Details
Timeline
Interventions
Adding PRP to wound bed during surgical debridement