At a glance
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A Prospective, Double-blind, Randomized Pilot Study Evaluating the Effects of Toradol and Lyrica Verses Placebo for Pain Control After Donor Nephrectomy (TORPEDO)
In Brief
A Phase 2 clinical trial evaluating Ketorolac, Pregabalin, and 2 other interventions for Pain, Postoperative. Completed, enrolled 64 participants.
Detailed Summary
The investigators will assess how the use of toradol and pregabalin affects return to bowel function and see if there is a difference in length of hospital stay. Narcotic use can affect bowel function so the investigators hypothesize that use of Toradol will decrease delayed bowel function and aid in a patients discharge and reduction of hospital stay.
Study Details
Timeline
Interventions
Ketorolac was administered intravenously: 30 mg in the operating room, and 15 mg every 6 hours for 7 doses post-operatively.
Pregabalin was administered orally: 75 mg 30 minutes prior to operation.
Placebo oral capsule was administered orally 30 minutes prior to operation.
Saline was administered intravenously: once in the operating room, and every 6 hours for 7 doses post-operatively.