CI

At a glance

ClinicalIndex Comparison Record
N/ACompleted· 683 enrolled
Drug / intervention
Cardiac imaging in the PREFERS and CABG PREFERS cohorts +2 moreother
Likely dose
Not stated in record
Structured eligibility isn't available for this trial yet — see the full criteria in the Eligibility tab below.

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NCT03671122N/ACompleted
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PREFERS PREFERS (Preserved and Reduced Ejection Fraction Epidemiological Regional Study) Stockholm Heart Failure Study

Karolinska Institutet·observational·Posted Sep 14, 2018·Updated Mar 31, 2022

In Brief

An observational study evaluating Cardiac imaging in the PREFERS and CABG PREFERS cohorts, Biomarker analysis in the PREFERS and CABG PREFERS chorts, and 1 other intervention for Heart Failure, Diastolic and Heart Failure，Congestive. Completed, enrolled 683 participants across 1 site.

Detailed Summary

Heart failure (HF) with preserved (HFpEF) or reduced (HFrEF) ejection fraction is associated with poor prognosis and quality of life. While the incidence of HFrEF is declining and HF treatment is effective, HFpEF is increasing, with no established therapy. PREFERS Stockholm is an epidemiological study with the aim of improving clinical care and research in HF and to find new targets for drug treatment in HFpEF starting with a cardiac biopsy study in elective CABG patiens.

Study Details

Study Typeobservational
Allocation--
Masking--
Primary Purpose--
ConditionsHeart Failure, Diastolic, Heart Failure，Congestive
CountriesSweden
CollaboratorsThe Swedish Research Council, Region Stockholm

Timeline

N/ACompletedFinished
201520162017201820192020202120222023202420252026
First PostedSep 14, 2018
Enrollment StartJan 1, 2015
Primary CompletionJan 31, 2021
Study CompletionFeb 28, 2021
TodayJul 2, 2026
Enrollment to primary: 6.1 yearsPosted 7.8 years ago

Interventions

Cardiac imaging in the PREFERS and CABG PREFERS cohortsother

performed at baseline and after 1 year

Biomarker analysis in the PREFERS and CABG PREFERS chortsother

blood samples will be taken for biomarker analysis at baseline and after 1 year

Cardiac biopsies in the CABG PREFERS cohortprocedure

myocardial biopsies from the right trium the left and right ventricles will be taken during elective CABG