CI

At a glance

ClinicalIndex Comparison Record
N/ACompleted· 22 enrolled
Drug / intervention
Home-based exercisebehavioral
Likely dose
Not stated in record
Structured eligibility isn't available for this trial yet — see the full criteria in the Eligibility tab below.

Standardized by ClinicalIndex from the ClinicalTrials.gov record · verify against the source.

Search/NCT03672396
NCT03672396N/ACompleted
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Feasibility Study of a Home-Based Exercise Intervention Program for Patients With Metastatic Castration-Resistant Prostate Cancer Receiving Androgen Deprivation Therapy (ADT)

UNC Lineberger Comprehensive Cancer Center·interventional·Posted Sep 14, 2018·Updated Apr 20, 2021

In Brief

A clinical study evaluating Home-based exercise for Castration-resistant Prostate Cancer and Androgen Deprivation Therapy. Completed, enrolled 22 participants across 2 sites.

Detailed Summary

This single arm, multi-site pilot study aims to evaluate the feasibility of recruiting and adherence to a 12 week home-based exercise intervention to be conducted in men with metastatic castration resistant prostate cancer (mCRPC) receiving androgen deprivation therapy (ADT). Thirty patients will be enrolled, with the expectation that 20-25 will complete all follow-up measures.

Study Details

Study Typeinterventional
Allocation--
Masking--
Primary Purpose--
ConditionsCastration-resistant Prostate Cancer, Androgen Deprivation Therapy
CountriesUnited States
CollaboratorsWake Forest University Health Sciences

Timeline

N/ACompletedFinished
2017201820192020202120222023202420252026
First PostedSep 14, 2018
Enrollment StartApr 1, 2017
Primary CompletionDec 31, 2019
TodayJul 2, 2026
Enrollment to primary: 2.8 yearsPosted 7.8 years ago

Interventions

Home-based exercisebehavioral

The intervention consists of aerobic and strength training \~3 times per week for 12 weeks with each session lasting 1 hour. The progressive aerobic exercise will involve walking that varies from from 15 to 30 minutes done 2-4 times per week at an intensity from 40% to 65% of heart rate reserve. Therabands elastic bands will be used to perform 12 to 15 repetitions per exercise. Once a participant can comfortably complete 15 repetitions for all prescribed sets, they will increase resistance by moving up to the next band. The training volume increased from 1 set per exercise on week 1 to 3 sets by week 12.