CI

At a glance

ClinicalIndex Comparison Record
Phase 2Completed· 19 enrolled
Drug / intervention
Mupirocin +3 moredrug
Likely dose
Mupirocin 30mgfrom record
Structured eligibility isn't available for this trial yet — see the full criteria in the Eligibility tab below.

Standardized by ClinicalIndex from the ClinicalTrials.gov record · verify against the source.

Search/NCT03673956
NCT03673956Phase 2Completed
CompareCT.gov

Topical Antibiotics in Chronic Rhinosinusitis

Mayo Clinic·interventional·Posted Sep 17, 2018·Updated Apr 20, 2022

In Brief

A Phase 2 clinical trial evaluating Mupirocin, Tobramycin, and 2 other interventions for Chronic Rhinosinusitis (Diagnosis). Completed, enrolled 19 participants across 1 site.

Detailed Summary

Researchers are trying to find out if patients develop antibiotic resistant organisms after the use of topical antibiotics in the treatment of chronic rhinosinusitis.

Study Details

Study Typeinterventional
Allocation--
Masking--
Primary Purpose--
ConditionsChronic Rhinosinusitis (Diagnosis)
CountriesUnited States
Collaborators--

Timeline

Phase 2CompletedFinished
20192020202120222023202420252026
First PostedSep 17, 2018
Enrollment StartSep 26, 2018
Primary CompletionFeb 1, 2021
TodayJul 2, 2026
Enrollment to primary: 2.3 yearsPosted 7.8 years ago

Interventions

Mupirocindrug

30mg capsules dissolved in a standard 240mL saline irrigation rinse and self-administered through nasal saline irrigation twice per day over 30 days.

Tobramycindrug

240mg capsules dissolved in a standard 240mL saline irrigation rinse and self-administered through nasal saline irrigation twice per day over 30 days.

Levofloxacindrug

240mg capsules dissolved in a standard 240mL saline irrigation rinse and self-administered through nasal saline irrigation twice per day over 30 days.

Vancomycindrug

240mg capsules dissolved in a standard 240mL saline irrigation rinse and self-administered through nasal saline irrigation twice per day over 30 days.