At a glance
ClinicalIndex Comparison RecordStandardized by ClinicalIndex from the ClinicalTrials.gov record · verify against the source.
Improving Cognition in People With Progressive Multiple Sclerosis: A Multi-Arm, Randomized, Blinded, Sham-Controlled Trial of Cognitive Rehabilitation and Aerobic Exercise.
In Brief
A clinical study evaluating Cognitive Rehabilitation, Sham Exercise, and 2 other interventions for Multiple Sclerosis, Primary Progressive and Cognitive Impairment. Completed, enrolled 309 participants across 1 site.
Detailed Summary
Given that up to 70% of people with secondary progressive MS are cognitively impaired, the search for effective treatments is considered a priority by people living with the disease. This proposal will address the effectiveness of cognitive rehabilitation (CR) and exercise, either alone, or in combination in this regard. A team of MS researchers has been assembled from the USA, Canada, the United Kingdom, Italy, Denmark, Germany and Belgium for this. A total of 360 people with progressive MS will make up the sample. Brain MRIs will be undertaken in a third of the sample before and after the 12 weeks of treatment to document the functional changes that are expected to occur with symptom improvement.
Study Details
Timeline
Interventions
RehaCom software Information processing speed and attention modules
Sets of balance and stretching exercises
Kompozer software 24 session module consisting of basic internet searches
Recumbent NuStep Bike Aerobic cycling