At a glance
ClinicalIndex Comparison RecordPhase 1Completed· 12 enrolled
Drug / intervention
Estradiol patchdrug
Likely dose
Not stated in record
Structured eligibility isn't available for this trial yet — see the full criteria in the Eligibility tab below.
Standardized by ClinicalIndex from the ClinicalTrials.gov record · verify against the source.
The Interaction Between Diabetes and Estradiol on Human Brain Metabolism in Postmenopausal Women
In Brief
A Phase 1 clinical trial evaluating Estradiol patch for Diabetes Type 2 and Dementia. Completed, enrolled 12 participants across 1 site.
Detailed Summary
The primary aim of this study is to test whether type 2 diabetes interacts with estradiol on brain metabolism in vivo in humans. This will be accomplished by imaging brain metabolism using positron emission tomography before and after short-term administration of transdermal 17β-estradiol in 10 postmenopausal women with diabetes and 10 non-diabetic postmenopausal women.
Study Details
Study Typeinterventional
Allocation--
Masking--
Primary Purpose--
ConditionsDiabetes Type 2, Dementia
CountriesUnited States
CollaboratorsNational Institute on Aging (NIA)
Timeline
Phase 1CompletedFinished
20192020202120222023202420252026
First PostedSep 2018
Enrollment StartMay 2019
Primary CompletionJul 2021
TodayJul 2026
First PostedSep 24, 2018
Enrollment StartMay 13, 2019
Primary CompletionJul 19, 2021
TodayJul 2, 2026
Enrollment to primary: 2.2 yearsPosted 7.8 years ago
Interventions
Estradiol patchdrug
transdermal 17β-estradiol patch